Two persons were killed and four were injured in two separate road accidents in the district today. The deceased were identified as Manpal (26) and Keshav Singh (40). Both were on their way to Madhya Pradesh as part of the Kanwar Yatra, when an unidentified vehicle ran over them early in the morning today, police said. In another similar mishap, around midnight, four Kanwariyas were injured after being hit by a vehicle. Both the incidents occurred on Agra-Mumbai national highway, the police said.